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Narito Tateishi Selected Research

ONO2506

8/2006Arundic Acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice.
6/2005Modulation of astrocytic activation by arundic acid (ONO-2506) mitigates detrimental effects of the apolipoprotein E4 isoform after permanent focal ischemia in apolipoprotein E knock-in mice.
7/2004Attenuation of a delayed increase in the extracellular glutamate level in the peri-infarct area following focal cerebral ischemia by a novel agent ONO-2506.
6/2002Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: suppression of astrocytic activation by a novel agent (R)-(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits.

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Narito Tateishi Research Topics

Disease

5Infarction (Infarctions)
06/2005 - 06/2002
3Gliosis
08/2006 - 09/2004
3Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
06/2005 - 06/2002
2Ischemia
05/2006 - 06/2005
2Neurologic Manifestations (Neurological Manifestations)
06/2005 - 06/2002
1Amyloidosis
08/2006
1Inflammation (Inflammations)
02/2006
1Brain Ischemia (Cerebral Ischemia)
07/2004

Drug/Important Bio-Agent (IBA)

4ONO2506IBA
08/2006 - 06/2002
3Proteins (Proteins, Gene)FDA Link
08/2006 - 09/2004
2Messenger RNA (mRNA)IBA
05/2006 - 07/2004
2EnzymesIBA
02/2006 - 06/2002
2Glial Fibrillary Acidic ProteinIBA
06/2005 - 06/2002
2S100 Calcium Binding Protein beta SubunitIBA
07/2004 - 06/2002
1Amyloid (Amyloid Fibrils)IBA
08/2006
1Amyloid beta-PeptidesIBA
08/2006
1LigandsIBA
05/2006
1ApolipoproteinsIBA
06/2005
1Apolipoprotein E2IBA
06/2005
1Apolipoprotein E4IBA
06/2005
1Apolipoprotein E3IBA
06/2005
1Protein Isoforms (Isoforms)IBA
06/2005
1Hematoxylin (Haematoxylon)IBA
09/2004
1Eosine Yellowish-(YS) (Eosin)IBA
09/2004
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
09/2004
1Glutamic Acid (Glutamate)FDA Link
07/2004
1Pharmaceutical PreparationsIBA
07/2004
1Biotin (Vitamin H)FDA Link
06/2002
1CytokinesIBA
06/2002
1DeoxyuridineIBA
06/2002
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
06/2002
1triphosphoric acid (triphosphate)IBA
06/2002
1Monoclonal AntibodiesIBA
06/2002

Therapy/Procedure

1Intravenous Administration
06/2002